Guest Editorial 2021 Custom Integrated Circuits Conference

This Special Section of the IEEE Journal Solid-State Circuits (JSSC) features expanded versions key articles presented at 2021 Custom Integrated Conference (CICC), which for second time in a row was fully virtual due to coronavirus pandemic. Originally planned be held Austin, TX, USA, unpredictability COVID-19 quickly lead conference organization decide (again) go format from April 25 30, 2021. With all experience previous year, where CICC first Society (SSCS) virtual, and that subsequent SSCS other conferences, it comparatively smooth sailing.